Propionate metabolism in a human pathogenic fungus: proteomic and biochemical analyses

IMA Fungus

Table 1 Identity of Paracoccidioides spp. MCC enzymes when compared with functionally characterized enzymes

Enzymes	*An/Pl*	*An/Pb03*	*An/Pb18*	*Af/Pl*	*Af/Pb03*	*Af/Pb18*
PCL	74%	74%	74%	75%	74%	74%
MCS	78%	78%	78%	81%	81%	81%
MCD	78%	78%	79%	78%	78%	78%
MCL	77%	77%	74%	78%	78%	76%

A. nidulans (An), A. fumigatus (Af), P. lutzii (Pl), P. americana PS3 (Pb03) e P. brasiliensis senso stricto (Pb18). PCL propionyl-CoA ligase, MCS methylcitrate synthase, MCD methylcitrate dehydratase, MCL methylisocitrate lyase

ISSN: 2210-6359

Enzymes	*An/Pl*	*An/Pb03*	*An/Pb18*	*Af/Pl*	*Af/Pb03*	*Af/Pb18*
PCL	74%	74%	74%	75%	74%	74%
MCS	78%	78%	78%	81%	81%	81%
MCD	78%	78%	79%	78%	78%	78%
MCL	77%	77%	74%	78%	78%	76%

Enzymes	*An/Pl*	*An/Pb03*	*An/Pb18*	*Af/Pl*	*Af/Pb03*	*Af/Pb18*
PCL	74%	74%	74%	75%	74%	74%
MCS	78%	78%	78%	81%	81%	81%
MCD	78%	78%	79%	78%	78%	78%
MCL	77%	77%	74%	78%	78%	76%

Enzymes	*An/Pl*	*An/Pb03*	*An/Pb18*	*Af/Pl*	*Af/Pb03*	*Af/Pb18*
PCL	74%	74%	74%	75%	74%	74%
MCS	78%	78%	78%	81%	81%	81%
MCD	78%	78%	79%	78%	78%	78%
MCL	77%	77%	74%	78%	78%	76%